Orexigen claims weight-loss pill is effective - The Money Times
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Contrave is a weight loss drug that combines Wellbutrin (bupropion) which is an antidepressant and the sustained-release version of naltrexone. (Fri Jan 09 04:34:04 2009 PST)
Orexigen drug shows 9.3 pct weight loss, shrs fall
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(US) Contrave is a pill that combines the antidepressant Wellbutrin. (Thu Jan 08 18:34:38 2009 PST)
[also iii6605]
Orexigen(R) Therapeutics Announces First of Four Phase 3 Trials of ...
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(US) (Nasdaq: OREX) today announced that the first of four Phase 3 trials of its lead investigational product Contrave(R) (naltrexone sustained release (SR)/bupropion SR) met its co-primary and key secondary endpoints, showing a significant reduction in body weight, improvements in markers of cardiovascular risk and reductions in selected food craving measures. Th... (Thu Jan 08 15:49:24 2009 PST)
[also sev.prnewswire6554]
Market Report -- In Play (OREX)
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(US) The overall safety profile of Contrave was consistent with its individual components, naltrexone and bupropion, two drugs that have been used separately in patients for over 20 years. (Thu Jan 08 14:34:56 2009 PST)
Obesity Drug From Orexigen Helps Patients Lose Weight in Pivotal ...
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The study, the first of four trials examining the effects of a long-lasting combination of naltrexone and bupropion, showed that patients lost an average of 20.3 pounds (9.3 percent of their weight) when they took the drug and followed an intense diet and behavior modification program. ... (Thu Jan 08 14:34:56 2009 PST)
Orexigen granted new patent for obesity drug
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(US) It is a companion to the Weber/Cowley composition patent which was issued by the US Patent and Trademark Office in May 2008 and broadly covers sustained release compositions of bupropion and naltrexone combined in a single dosage form. (Wed Jan 07 03:05:35 2009 PST)